Sleep Circuit
نویسندگان
چکیده
منابع مشابه
A Drosophila Circuit Feels the (Sleep) Pressure
How sleep is homeostatically regulated remains a mystery. In this issue of Neuron, Donlea et al. (2014) provide evidence in Drosophila that a set of sleep-inducing neurons require Crossveinless-c, a specific Rho-GTPase-activating protein (Rho-Gap), to alter their membrane excitability in response to sleep deprivation.
متن کاملSWS promoting MHb-IPN-MRN circuit opposes the theta promoting circuit, active wake and REM sleep
Hippocampus was connected to medial habenula (MHb) by multisynaptic axonal tracts in my previous DTI study. These probabilistic tracts linked hippocampus to septum, and amygdala to bed nucleus of stria terminalis (BNST). The axons from septum and BNST passed by anteromedial thalamic nucleus (AM) to MHb, then from MHb to pineal gland, known for control of circadian cycles and sleep. Question is ...
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General anesthesia remains a mysterious phenomenon, even though a number of compelling target proteins and processes have been proposed [1]. General anesthetics such as isoflurane abolish behavioral responsiveness in all animals, and in the mammalian brain, these diverse compounds probably achieve this in part by targeting endogenous sleep mechanisms [2, 3]. However, most animals sleep [4], and...
متن کاملThalamic Circuit Mechanisms Link Sensory Processing in Sleep and Attention
The correlation between sleep integrity and attentional performance is normally interpreted as poor sleep causing impaired attention. Here, we provide an alternative explanation for this correlation: common thalamic circuits regulate sensory processing across sleep and attention, and their disruption may lead to correlated dysfunction. Using multi-electrode recordings in mice, we find that rate...
متن کاملSWS- Promoting MHb-IPN-MRN Circuit Opposes the Theta- Promoting Circuit, Active Wake and REM Sleep. A Circuit-Based Model of Functional Properties
Hippocampus was disynaptically connected to medial habenula (MHb) in my previous DTI study. Observed probabilistic axonal tracts linked hippocampus to septum, and amygdala to bed nucleus of stria terminalis (BNST). Septum and BNST projected to MHb, then from MHb to pineal gland. Question is what is the MHb doing and why it receives information from hippocampus via septum? Thus, this study explo...
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ژورنال
عنوان ژورنال: Science
سال: 2014
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.344.6182.341-b